Introducing Origen™ by Cellino. Preserve your healthiest cells today. Join the waitlist →

Your Cells Are
Your Future

We reset your cells to a youthful biological state and securely store them for future regenerative therapies. Your biology, preserved at its healthiest starting point.

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"We live 80-year lives in bodies built for 40. For the first time, we can do something about it."

— Nabiha Saklayen, PhD, Co-Founder & CEO

"A breakthrough in personalized cell preservation."

Forbes

"Cellino is rewriting the rules of regenerative medicine."

WSJ

"The next frontier in longevity — your own cells."

TechCrunch
★★★★★ 5.0 · Early Access Reviews

Origen™

iPSC Reserve by Cellino

Your personalized cell preservation service. Origen collects a simple blood sample, validates your cells through rigorous quality testing, and cryopreserves them in state-of-the-art medical facilities, building your foundational cell bank for whatever the future of medicine brings.

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★ ★ ★ ★ ★
Seamless From Start to Finish

"I've been following cell therapy for years. Origen is the first product that made iPSC reserve accessible and actually explained the science. The process was seamless."

Dr. Sarah K. Verified
Simple
Blood Draw
Clinical-Grade
Storage
You Own
Your Cells

What You Get

  • Minimally invasive sample collection (15-minute blood draw at a partner clinic)
  • Rigorous PBMC quality testing & validation
  • Long-term cryopreservation in medical-grade facilities
  • Access to your cells when future therapies become available
  • Annual health & viability reports
  • Founding Cellino Concierge membership: dedicated support for cell status updates, therapy access, and priority onboarding as treatments go live
$120M+
Raised from Khosla, 8VC, Felicis, Bayer, and ARPA-H
FDA
Advanced Manufacturing Technology designation
10+
Patents protecting our approach
14+
Years of Nobel Prize-winning research in regenerative medicine
115+
Clinical trials globally exploring PSCs for therapeutic use

How It Works

A simple blood draw. 15 minutes at a partner clinic. From there, Cellino handles everything.

[01]

Blood Draw

A simple 15-minute blood draw at a partner clinic near you. That's all we need from you -- one sample to start the entire process.

~15 minutes - Your only step
[02]

Selection, Reprogramming & Expansion

Cellino isolates your key cells, reprograms them into stem cells using proprietary laser technology, and carefully expands them into a robust supply.

Cellino handles everything
[03]

Banking, QC & Report

Your validated cells are cryopreserved in independent, medical-grade facilities. Each cell line is rigorously tested, and you receive a full report confirming storage readiness.

Stored for the future
See the full 7-step process
01
Blood Draw

A simple blood draw captures the cells needed to create your personalized stem cell line.

02
Selection

Key cells are gently separated from your blood, preserving quality and readiness.

03
Reprogramming

Cells are reprogrammed to stem cells capable of becoming any cell type using laser-based precision.

04
Expansion

Stem cells are carefully grown to build a robust, long-term supply.

05
Banking

Cells are cryopreserved in independent, medical-grade biobanking facilities.

06
Quality Control

Rigorous checks confirm identity, health, and consistency of each cell line.

07
Report

You receive a clear summary confirming successful creation and storage readiness.

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See how your cells become future-ready in under two minutes.

The complete journey from sample to secure, clinical-grade storage.

A Different Class of Cell Banking How iPSC banking compares to today's legacy options

Origen™ by Cellino Egg Freezing / Cord Blood
Available at any age ✓ ✕
Covers your whole body ✓ ✕
Can become any cell type ✓ ✕
Simple blood draw ✓ Varies
Genetically matched to you ✓ ✓
Clinical trials active now ✓ Limited
Grows in value as new therapies launch ✓ ✕
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TWO PATHS FROM ONE BLOOD DRAW

Your cells unlock two things, not one

Both start from the same blood draw. Both get more valuable over time.

Research Use

Your cellular twin

A crash test dummy for your health, made from your actual cells. Not frozen storage. A living model of you: actively differentiated for drug screening, disease modeling, and biological aging comparison.

Drug screening · Disease modeling · Personalized insights · Longevity research
Clinical Path

Cell & tissue replacement

As iPSC-derived therapies gain approval, your banked PBMCs become the starting material. Retinal cells for vision. Neurons for Parkinson's. Cartilage for joints. Made from you, for you. No starting from scratch at 60 with 60-year-old cells.

Autologous therapies · Tissue engineering · Clinical trial readiness
SCIENTIFIC FOUNDATION

The Science Behind Your Cells

Four breakthrough technologies work together to turn a simple blood draw into your most valuable biological asset.

01

iPSC Science

Your adult cells are reprogrammed back to a pluripotent state, capable of becoming any cell type in your body. Built on Yamanaka factors, the Nobel Prize-winning breakthrough behind personalized regenerative medicine.

Nobel Prize · 2012
02

Laser-Based Reprogramming

Precise, non-contact laser control at the single-cell level initiates reprogramming without manual handling.

Single-cell precision
03

Image-Guided Bioprocessing

High-resolution imaging monitors every cell's morphology and behavior in real time throughout reprogramming and expansion. Quality decisions are based on what's actually happening, not batch averages.

Real-time quality control
04

AI & Machine Learning

Machine learning models interpret imaging data and drive adaptive process control. Automated decision-making replaces manual judgment to deliver consistent, reproducible outcomes at scale.

Automated at scale
ACTIVE PROGRAMS

Our manufacturing platform is actively supporting therapy development across multiple indications.

Parkinson's

Mass General Brigham

Phase 1 enrolling. First hospital-based deployment of our Nebula™ platform. iPSC-derived dopaminergic neurons.

Cardiovascular

Karis Bio

First-in-human study underway in South Korea. US trial planned. iPSC-derived endothelial cells for peripheral artery and coronary artery disease.

Spinal cord injury

Matricelf

IND expected 2026. iPSC lines delivered and differentiated for engineered neural tissue.

Built on Nobel Prize Science. Validated by the FDA.

Our platform holds FDA Advanced Manufacturing Technology designation, builds on the 2012 Nobel Prize in Physiology or Medicine, and is actively supporting therapy development at Mass General Brigham, Karis Bio, and Matricelf.

Nobel Prize Science

In 2012, Shinya Yamanaka shared the Nobel Prize for discovering that adult cells can be reprogrammed into pluripotent stem cells. Your cells can become any cell type: heart, brain, retina, cartilage, blood, skin.

Laser Reprogramming

Cellino's proprietary laser-based platform enables precise, non-contact reprogramming at the single-cell level. No manual handling, no destructive intervention. Just precision manufacturing at scale.

FDA Designated

Our platform holds FDA Advanced Manufacturing Technology designation with active clinical partnerships with Mass General Brigham, Karis Bio, and Matricelf. This isn't theoretical. It's happening now.

Clinical-Grade Storage

Your cells are cryopreserved in independent, regulated biobanking facilities with redundant systems and continuous monitoring. Not in our offices, but in purpose-built medical infrastructure.

Your Cells, Your Ownership

Your biological material never gets used for anything without your explicit consent. You decide when and how to use your cells. Your cells, your ownership, your future.

The Clock Is Ticking

Your cells age with you. Every single day. Banking them now means you'll have the youngest, healthiest starting material when therapies reach your condition. The alternative is starting from scratch with older cells.

What Experts Are Saying

Leading scientists on the future of iPSC technology
"

iPSC technology is for patients, and the more scientists who build on it, the faster we can help those who live with chronic or life-threatening diseases.

Shinya Yamanaka, MD, PhD
Nobel Laureate in Physiology or Medicine, 2012. Discovered iPSC reprogramming.
Gladstone Institutes
"

We can take skin cells and grow human cortex in a dish. Induced pluripotent stem cells have given us a window into human development unlike anything we had before. It's a game-changer.

Arnold Kriegstein, MD, PhD
Director, Eli & Edythe Broad Center of Regeneration Medicine, UCSF
UC San Francisco
"

iPSCs have the potential to repair or replace damaged tissues and treat a range of diseases considered incurable, including Parkinson's, heart failure, spinal cord injuries and diabetes.

Constantinos Chronis, PhD
Assistant Professor of Biochemistry & Molecular Genetics, University of Illinois Chicago
ASBMB

The Founders

Cellino was founded by scientists who met at Harvard, driven by a shared belief: personalized regenerative health should be accessible to everyone.

Marinna Madrid and Nabiha Saklayen, Co-Founders of Cellino
Nabiha Saklayen, PhD Co-Founder & CEO
Marinna Madrid, PhD Co-Founder & CPRO
NS
Nabiha Saklayen, PhD
Co-Founder & CEO

Harvard-trained physicist who pioneered laser-enabled precision for complex biological processes. Inventor of cellular laser editing techniques and recipient of the first Tory Burch Fellowship at the Innovative Genomics Institute (IGI).

MIT TR 35 Under 35 — Pioneer Forbes 30 Under 30 — Healthcare PhD Physics — Harvard HHMI International Fellow
MM
Marinna Madrid, PhD
Co-Founder & CPRO

Applied physicist who co-invented laser-based intracellular delivery techniques at Harvard. Leads Cellino's regulatory strategy, including the FDA-granted Advanced Manufacturing Technology designation. Authored the first review paper on autologous iPSC-based cell therapies.

Forbes 30 Under 30 — Healthcare FDA Advanced Mfg. Designation PhD Applied Physics — Harvard Harvard Graduate Prize Fellow HMS Catalyst Accelerator Grant Multiple Patents & Publications
The Case for Now

Why Bank Now?

If you believe in a future where your own cells can repair, replace, and regenerate, the smartest move you can make is to preserve your youngest starting material today.

Your Lowest Somatic Mutation Burden

Every day that passes, your cells accumulate more DNA mutations. Right now, today, is the youngest your cells will ever be. Banking now captures them at their lowest mutation burden, the best possible starting material for future therapies.

Be First in Line

iPSC-derived therapies are entering clinical trials now. By banking today, you'll be among the first to access these therapies when they become available. Your cells will already be preserved, validated, and ready to go.

Part of Building the Infrastructure

By joining now, you're not just preserving your biology. You're helping build the infrastructure for a new era of medicine. Early members get frequent updates on breakthroughs and direct access to iPSC therapies as they launch.

Healthy & Active for the Years Ahead

This isn't about fear. It's about agency. We get to remain healthy and active for the years we are on earth. Banking your cells is the proactive step that gives you options when you need them most.

"In 30 years, there is going to be a way to replace the parts of your body that fail you. If you bank your iPSCs now, you will be first in line to access it. In 30 years, would you wish you had your youngest and best starting materials?"

What You Might Be Wondering

How does the process work? +
A standard blood draw at a partner clinic near you (15 minutes, no surgery). Your immune cells are isolated and cryopreserved. From there, they can be reprogrammed into iPSCs on our automated manufacturing platform and banked for research use now and clinical therapies as they arrive.
When can I actually get a therapy? +
iPSC-derived therapies are in clinical trials now. Timelines to broad availability depend on trial outcomes and regulatory approval, but banking your cells today means you have the starting material ready when therapies reach your condition. The alternative is starting from scratch with older, degraded cells.
What does it cost? +
Pricing details will be shared during the reservation process. We're designing tiers that make this accessible to early adopters while reflecting the clinical-grade quality of what's being preserved and manufactured.
What exactly is an iPSC? +
If stem cells were cars, iPSCs would be the Formula 1 tier. They're your own adult cells, reprogrammed back to an embryonic-like state, meaning they can become virtually any cell type: heart, brain, retina, cartilage, blood, skin. Genetically matched to you. The science shared a Nobel Prize in 2012 and clinical trials are running globally.
How is this different from egg freezing or cord blood? +
Egg freezing preserves fertility. Cord blood is collected at birth and limited to certain blood disorders. Neither covers the rest of your body for the rest of your life. Origen starts from a simple blood draw, available at any age, and produces cells that can become any tissue type. It's a fundamentally different category.
Where's the proof this works? +
Japan treated the first patient with iPSC-derived cells in 2014. Trials are now active globally for Parkinson's, macular degeneration, heart failure, spinal cord injury, and cancer. Our platform has FDA Advanced Manufacturing Technology designation and active clinical partnerships with Mass General Brigham, Karis Bio, and Matricelf.
Will my doctor do the therapy? Will insurance cover it? +
As iPSC therapies move through clinical trials and gain regulatory approval, they'll become available through healthcare providers. Insurance coverage will evolve alongside approvals. Banking your cells now ensures you have the starting material ready, regardless of how the delivery and coverage landscape develops.
What happens to my cells if the company shuts down? +
Your cells are stored in independent, regulated biobanking facilities, not in our offices. In any scenario, your biological material remains yours and transfer protocols are in place to ensure continuity of storage. Your cells, your ownership, always.
Reserve Your Spot

We Are Not Getting Younger

But for the first time, we have a choice. Simple blood draw. Clinical-grade storage. This is the one decision you can't make later.

Built for the future of regenerative medicine.

Join the Waitlist

Founding cohort · By invitation

The information on this page is for educational and informational purposes only and does not constitute medical advice, diagnosis, or treatment. Cellino does not claim that iPSC banking will treat, cure, or prevent any disease. iPSC-derived therapies are investigational and subject to clinical trial outcomes and regulatory approval. Individual results may vary. The expert quotes presented reflect publicly available statements and do not constitute endorsements of Cellino or its products. Cellino is not a healthcare provider. Always consult a qualified healthcare professional before making decisions about your health. Past scientific achievements and ongoing clinical trials do not guarantee future therapeutic availability or outcomes.

Save Your Cells — Cellino